BioBRB

What is BioBRB ?

Basic information

BioBRB is a food ingredient developed based on our unique platform technology.
The main component of BioBRB (Toloran4) is an immunopolysaccharide, more specifically, a water-soluble beta-glucan. The reason why Toloran4 has a different function from other beta-glucans has not yet been elucidated, but it is thought that it is because, structurally, glucose is substituted with other sugars, unlike the well-known beta-glucans, and some contain glucuronic acid. do.
The main component of BioBRB (Toloran4) is an immunopolysaccharide, more specifically, a water-soluble beta-glucan. The reason why Toloran4 has a different function from other beta-glucans has not yet been elucidated, but it is thought that it is because, structurally, glucose is substituted with other sugars, unlike the well-known beta-glucans, and some contain glucuronic acid. do.
Cereal beta-glucan, the main active ingredient of BioBRB, is very complex compared to yeast-derived beta-glucan made from pure glucose, and is a water-soluble polysaccharide, which is substantially different from other commercially available beta-glucans

Brand new acidic
cereal beta-glucan

β-Glucan is a water-soluble polysaccharide consists of glucose units. Glucose monomers are linked via β-(1→3) glycosidic bonds in bacteria and algae whereas glucose monomers are linked via β-(1→3) and β-(1→6) glycosidic bonds in yeast and mushrooms. In oats and barley, glucose monomers are linked via β-(1→4) and β-(1→3) glycosidic bonds.
In general, beta-glucan is loosely defined, so if there is some beta-glucosidic bond of glucose, it is called beta-glucan. Therefore, even if a significant amount of glucose is substituted with other sugars among beta-glucans, it is also called beta-glucan. Beta glucan contained in BIoBRB is a polysaccharide in which glucose has been substituted with significantly different monosaccharides and various other modifications have been made.
Until recently, cereal beta-glucan had little immune-stimulating activity, and only the function of dietary fiber was mainly studied. However, beta-glucan contained in BioBRB is a polysaccharide with very high immune-stimulating activity. This is thought to be because cereal beta-glucan also differs from grain to grain and depending on the extraction method.

Manufacturing
Process and Products

Bioconverted BRB is immediately freeze-dried and sold under the product name BioBRB. In addition, recently, active ingredients are purified and developed into pharmaceuticals.

Features of BioBRB

BioBRB has high immune activity and is currently sold without further purification, and many studies have been conducted using this material.
Currently, the company is also developing products with additional purified materials, which will be marketed upon completion of our new manufacturing facility.
In addition, we have built our own unique platform technology by convergence of life science-related technologies in various fields, and based on this, we are developing and commercializing various natural/microbial bio-materials.
In addition, we are developing medicines that improve innate immunity by purifying immune polysaccharides with high immune activity.
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01High Potency

BioBRB shows the highest immune activity among food ingredients currently available on the market.

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02Safety

Safety has been confirmed in many animal tests and toxicity tests, and safety has been confirmed as it has been sold on the market for about 10 years since its development.

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03Versatility

Since immunity is one of the most basic functions of the human body, it has various effects, so it can be used for a variety of symptoms.

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04Cost

It has the best cost-effectiveness ratio among current commercial products.

Summary of BioBRB

Heading #1
Origin
Black rice bran
Active ingredient
Toloran4
Structure
Beta-glucan
Acidic polysaccharide
Mode of Action
  1. TLR4 mediated immune cell activation
  2. Increase phagocytosis and phagosomal degradation

Suggestions for selection
of immune boosters

High activity
The most important thing in daily use of an immunization product is that it must be highly active. Only high activity can produce a variety of effects. However, it is not possible to measure the efficacy of all immune materials in one way. Immune products are largely divided into water-soluble products and granular products. Of these, water-soluble products are generally very easy to test in vitro. However, since it is very difficult to test a particle-type product, it cannot be tested under the same experimental conditions, so the results of these two types of substances should only be compared in animal experiments, not in vitro experiments.
Substances that do not induce inflammation
In the development process, there were many candidates that caused inflammation among the ingredients that boost immunity. Most of the products on the market are excellent products that do not cause inflammation, but most of them are low-active substances, so inflammation is often not a problem. In fact, most supplements do not cause inflammation. However, some of the products that increase immunity without being immune polysaccharides can cause inflammation.
Products with various effects
Immunity has many different effects on the human body, so even if you consume immune products, the effects will vary. Therefore, it cannot be said to be good for only one symptom. It is also desirable to select immune products according to their efficacy. In particular, it helps recover from fatigue, balances immunity, and has anti-cancer effects. You can choose products that are good for recovering from hangovers or fatigue with Hantang.
If economical is considered, check if it is also used in livestock.
Good immune substances are also used as products of livestock (economic animals) because they are economical.